DSM Diagnosis of the First Psychosis Episode: Past, Present, and Future
Rajiv Tandon, MD, Dost Ongur, MD, and Matcheri Keshavan, MD
In this webinar, we will review the historical evolution of psychiatric diagnosis with special reference to psychosis disorders by:
Examining the development of the DSM framework, highlighting key conceptual shifts, strengths, and enduring limitations in classification;
Critically evaluating the current state of psychosis nosology, including major challenges such as heterogeneity, limited biological validity, and gaps in clinical utility, while discussing an integrative framework for today’s clinicians to use; and
Envision future directions for psychiatric classification, focusing on the integration of biomarkers, dimensional approaches, and hybrid categorical–dimensional models to advance precision psychiatry and improve patient outcomes.
Matcheri Keshavan, MD, Stanley Cobb Professor and Academic Head of the Harvard Department of Psychiatry at Beth Israel Deaconess Medical Center. Dr. Keshavan has conducted early psychosis intervention and research for nearly three decades. He founded one of the first early psychosis clinical programs in Pittsburgh in 1990 and has published over 600 papers and 4 books on psychotic and related disorders. He organizes educational conferences focused on early intervention in psychosis and has been developing cognitive enhancement therapy (CET) for schizophrenia. Dr. Keshavan is the editor of Schizophrenia Research and is on the editorial board of several other journals. He received the 2019 Research Award from the National Alliance on Mental Illness (NAMI).
Rajiv Tandon, MD, is Professor Emeritus of the Department of Psychiatry at the Western Michigan University Homer Stryker M.D. School of Medicine and a board-certified psychiatrist. He is a graduate of the All India Institute of Medical Sciences, New Delhi, India. He completed his residency in psychiatry at the National Institute of Mental Health and Neuro Sciences (NIMHANS) and at the University of Michigan Medical Center, Ann Arbor, Michigan. He subsequently obtained a Master's degree in Clinical Research Design and Statistical Analysis from the University of Michigan School of Public Health and a diploma in Management Development from the Harvard Business School. He served on the faculty in the Department of Psychiatry at the University of Michigan from 1987-2004; in addition, he served as the Director of the Schizophrenia Program from 1987-2000 and Director of the Hospital and Community Services Division from 1996-2000.
Dost Öngür, MD, PhD, is currently the chief of the Division of Psychotic Disorders, responsible for three inpatient units, a residential facility, a PACT team, two specialty outpatient clinics, and a community support program. In addition to his clinical work, he receives funding from the National Institute of Mental Health and other sources for his research on the clinical manifestations and neurobiology of schizophrenia and bipolar disorder. Dr. Öngür is currently the William P. and Henry B. Test Professor of Psychiatry at Harvard Medical School and the author of more than 250 articles on research into the neurobiology of bipolar disorder and schizophrenia. He has won awards from McLean Hospital, Partners HealthCare (now Mass General Brigham), and Harvard Medical School for his teaching of medical students and residents and for mentoring. He also serves as the editor of JAMA Psychiatry, a premier journal in the field.